THE ODDESSI TRIAL

The ODDESSI Trial: Evidence, Findings & Systemic Implications

A decade of research on Open Dialogue in public mental health systems, published August 2026 in The Lancet Psychiatry.

Pilling, S., et al. (2026). Open Dialogue versus treatment as usual for adults presenting in crisis to mental health services in England (the ODDESSI Trial): a multisite cluster-randomised trial. The Lancet Psychiatry.

The Global Costs of the Current System

When someone experiences a mental health crisis in the traditional Western model, whether in Australia or the UK, they typically encounter a fragmented maze.

They might contact their GP or present to an emergency department. They may be triaged by a crisis team, and if things stabilise, they may be handed over to a community mental health team. Throughout this process, the individual often sees different clinicians each time and has to repeat their story again and again. Family and friends are rarely invited into the conversations, and notes are kept secret from the person they are about.

The human cost of this approach is profound. As highlighted in numerous international mental health inquiries, people consistently describe feeling lost, unheard, and treated like a diagnosis rather than a person. Families and other loved ones feel sidelined, staff feel overwhelmed, hospital beds overflow, and people are frequently detained against their will.

Before ODDESSI: What the Original Finnish Data Showed

In the 1980s, Jaakko Seikkula and his colleagues in Western Lapland did something radical. When someone was in crisis, they brought the person, their family, their friends, and clinical staff together in one room. They listened to everyone rather than relying solely on a clinician’s diagnosis. They made decisions together, kept the same team throughout the process, and stayed connected even after the crisis passed.

Research consistently associates the original Western Lapland model with strong long-term outcomes over its first decades of use. These figures come from naturalistic, non-randomised studies in Finland, not from ODDESSI, which was designed specifically to test whether these results would hold up in a large randomised trial within the NHS.

82%

NO RESIDUAL PSYCHOTIC SYMPTOMS LEFT AFTER 5 YEARS

86%

RETURNED TO STUDY OR WORK

29%

REQUIRED MEDICATION

The ODDESSI trial was built to answer a critical question: could an approach that originated in Western Lapland work at scale within a large, complex public health system like the UK NHS?

What is Open Dialogue?

Open Dialogue brings the person in crisis, their family and friends, and mental health staff together in one meeting. There are no hidden notes and no diagnoses handed down. It relies on genuine conversation aimed at understanding what is happening and finding a way forward together.

What is ODDESSI?

ODDESSI stands for Open Dialogue: Development and Evaluation of a Social Network Intervention for Severe Mental Illness.

It is the largest randomised controlled trial ever conducted on Open Dialogue.

The overarching research was led by Principal Investigator Professor Stephen Pilling (University College London) and Clinical Lead Dr Russell Razzaque, alongside a large team of academics, clinicians, and lived-experience researchers from across England. The full author list and study details are available via the official UCL ODDESSI Trial Hub.

The Trial at a Glance

 

  • The Scale: 494 participants took part in the main trial, 271 receiving Open Dialogue and 223 receiving standard care. Before launching the main study, researchers ran a smaller pilot study to see if recruiting people in the middle of a severe mental health crisis was even possible. During that pilot, they screened 362 people, , of whom 63 were assessed as eligible, proving the trial could work.

  • The Locations: Delivered across five NHS Trusts in England (North East London, Kent and Medway, Barnet, Enfield and Haringey, Camden and Islington, and Devon).

  • The Comparison: 32 neighbourhood clusters (groups of GP practices) were randomly assigned to deliver either Peer-Supported Open Dialogue or standard community crisis care.

  • The Timeline: The project spanned from 2017 to 2026. This included five phases of trial development and active research, followed by a strict two-year observation period for every participant after their initial crisis. Full results were published in August 2026.

The Difference: Peer-Supported Open Dialogue

A critical distinction of the ODDESSI trial was that it tested Peer-Supported Open Dialogue.

In the original Finnish model, network meetings were facilitated by traditional clinical staff (nurses, psychologists, psychiatrists) who had trained in dialogical practice. ODDESSI introduced a new dynamic. The trial explicitly trained peer practitioners to co-facilitate these meetings alongside clinicians. These were individuals with lived experience of mental health crises.

The research team hypothesised that this integration of lived experience would help flatten the clinical hierarchy. The aim was to ensure that the person in crisis was supported by someone who understood the territory of psychological distress from the inside out.

How the Trial Worked

The ODDESSI trial was not just one big test. It was built in five meticulous phases to ensure accuracy at every step.

  • Building the Model: The team designed exactly how meetings would run in clinical settings and created staff training programmes.

  • Testing Feasibility (The Pilot Phase): Before launching the full trial, researchers needed to know if a study of this magnitude was even possible in the busy NHS. They ran a pilot study to test if they could safely recruit and retain people experiencing an acute crisis. They screened 362 people, of whom 63 were assessed as eligible. This pilot met all its targets, and the results were released as a preprint in October 2025.

  • The Main Trial (Cluster Randomisation): With the pilot a success, the main trial began, recruiting 494 participants against an original target of 644. Instead of randomising individual patients, the researchers randomised entire neighbourhoods. 32 GP practice clusters across England were assigned to either Open Dialogue or standard care. Because Open Dialogue changes how a whole team works together, you cannot split a single crisis team in half and have them switch between two completely different ways of working from patient to patient. Cluster randomisation ensured each team delivered one approach consistently. Everyone was then followed for two years.

  • Process Evaluation: Qualitative researchers tracked what teams were actually doing day-to-day and how peer practitioners changed the culture.

  • Listening to Experiences: Researchers conducted in-depth interviews to understand what it actually felt like to receive or deliver the care.

The Trial Findings

The published data presents a dataset reflecting what occurred when care shifted toward network involvement and relational continuity:

  • Primary Outcome (Time to Relapse): The trial did not show a statistically significant difference in time to relapse between Open Dialogue and standard care over the two-year follow-up period.
  • Inpatient Hospital Admissions: Participants receiving Open Dialogue had significantly higher odds of avoiding hospital admissions, resulting in a substantial reduction in acute bed days.
  • Crisis Re-Referrals: Rates of re-referral back into crisis services were significantly lower in the Open Dialogue group.
  • User Experience: Participants reported significantly higher satisfaction, feeling listened to, respected, and involved in their decisions.
  • Social Network Size: The trial measured no statistically significant increase in the size or density of participants’ social networks over time.

Methodologically, participants and clinicians were not blinded to the intervention during the trial.

What Does This Mean?

ODDESSI marks a major milestone for relational mental health care. It moves the conversation beyond anecdote and gives our field robust empirical data to examine, debate, and build upon.

While the trial demonstrates that dialogical practice does not erase the recurrence of psychological distress, it points to the value of relational continuity: keeping people out of acute hospital beds, preventing crisis bounce-backs, and holding space with dignity.

Dialogue Room will be unpacking these results in the coming months.

Dive Deeper: Trial Mechanics & FAQ

All data collection is complete, and the research team has spent over two years analysing the results. The full findings are expected to be published in August or September 2026. We are watching things closely and this page will be updated as soon as the research is published. We have an exciting conversation planned with some of the team linked to ODDESSI as part of Humanising Systems in late September or early October.

What is the difference between Open Dialogue and traditional therapy? Open Dialogue is a way of organising an entire mental health service. It includes therapy through network meetings, but it also ensures immediate access, continuity with the same team, and the full integration of family. Traditional therapy is often limited to one person seeing one therapist for one hour a week.

Does Open Dialogue use medication? Yes. Open Dialogue does not refuse medication. However, medication is considered alongside listening and relationship building, not instead of them. While historical Finnish data showed fewer people needed long-term medication, this is considered a result of the relational approach, not because medication was actively withheld.

Is this only for psychosis? ODDESSI tested the approach specifically for people in acute crisis, which often involves psychosis but not always. Open Dialogue principles are now being used globally for a range of presentations including depression, anxiety, and relationship crisis.

How is Dialogue Room connected to ODDESSI?
Dialogue Room’s Associate Director, Mark Hopfenbeck, is one of the trial’s authors. Dialogue Room draws on Open Dialogue principles and the growing research base, including ODDESSI, to inform our practice.

  • Pilling, S., et al. (2026). Open Dialogue versus treatment as usual for adults presenting in crisis to mental health services in England (the ODDESSI Trial): a multisite cluster-randomised trial. The Lancet Psychiatry.

  • Goodwin, J., et al. (2022). Qualitative evaluation of peer-supported Open Dialogue in the NHS.

  • Pilling, S., et al. (2022). Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial. Contemporary Clinical Trials.

  • Pilling, S., et al. (2025). Open Dialogue compared to usual care for adults experiencing a mental health crisis: A feasibility study for the ODDESSI trial. medRxiv.

  • Alvarez-Monjaras, M., et al. (2023). The community mental health team fidelity scale: A measure of program fidelity of social networks interventions for severe mental illness. Frontiers in Psychology.

  • Sunthararajah, S., et al. (2022). Exploring patients’ experience of peer-supported open dialogue and standard care following a mental health crisis: Qualitative 3-month follow-up study. BJPsych Open.

  • Anestis, K., et al. (2025). Peer-supported Open Dialogue: A qualitative study of peer practitioners’ experiences and non-peer practitioners’ perspectives on peer involvement. BJPsych Open.

Explore Our Work

What started as a single vision in Australia, making Open Dialogue network meetings accessible to families across Australia, has slowly expanded into something much larger.

Dialogue Room: Where it Started

This is where it all began, in Australia. We started with a simple vision: making Open Dialogue network meetings accessible to families across Australia. From that foundation, we’ve slowly expanded into something larger, continually exploring different ways to bring dialogical practice into the way we live and work. Making it the default, not the exception.

Humanising Systems Podcast

A series of conversations exploring the intersection of human experience and the systems designed to support it. In October, we sit down with three individuals closely connected to ODDESSI to unpack the outcomes.

Dialogue Space

Dialogue Space is our free monthly global gathering that connects families, practitioners, and communities. Just genuine connection and the opportunity to experience what relational care actually feels like.

Global Forum

The Global Forum is a private, moderated online community launching soon where individuals, families, and practitioners can sit with uncertainty, engage in dialogue, share reflections, and learn from one another in real time.

Dialogue Room Portugal

This is our first international hub, operated in partnership with practitioners deeply rooted in dialogical practice. Families in Portugal can now access Open Dialogue network meetings in English and Portuguese.

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